Questions & Answers(Forums)Category: Bipolar DisorderHow is valproate (Depakote) used to treat bipolar I disorder?
Claire Voyant asked 3 weeks ago
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Charles O. Young answered 3 weeks ago

This anti-seizure medication also works to level out moods. It is faster acting than lithium for an acute episode of mania. It is also often used “off-label” for prevention of new episodes. As a mood stabilizer that can be used by a “loading dose” method — beginning at a very high dose — valproate allows the possibility of significant improvement in mood as early as four to five days.

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